Limited Health Risks in Performing Drug Reconstitution and Handling Tasks in Pharmacies—Results of an Occupational Risk Assessment Study

Source avec lien : Journal of Occupational and Environmental Medicine, 65(4). 10.1097/JOM.0000000000002781

Cet article présente la première étude multicentrique utilisant une approche basée sur le risque pour évaluer l’exposition professionnelle du personnel des pharmacies lors des tâches de manipulation des médicaments. Les stratégies de ventilation visant à réduire l’exposition peuvent être facilement mises en œuvre dans les pharmacies communautaires et hospitalières du monde entier.

Objective  Some drugs need processing before they can be administered or dispensed. We measured airborne exposure of pharmacy staff to small particles when performing these tasks. Methods  Reconstitution of powdered drugs in vials; crushing, splitting, and counting of tablets; and opening of capsules, using different ventilation strategies, were investigated in five pharmacies after in a worst-case approach. Airborne particulate matter was determined for a range of particles sizes. Results  Mean particle concentrations ranged from not detectable to 1.03 μg/m3 (<1 μm) and 589.7 μg/m3 (<10 μm). Dust exhaust made tasks safer. Most hazardous was pouring out tablets from a bulk supply, and least hazardous was reconstitution of a powder for injection. Conclusions  Occupational exposure during routine handling of drugs can occur, but the risks vary greatly with the nature and duration of the tasks. Lisez l’article

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