Source avec lien : Scientific Reports, 12(1). 10.1038/s41598-022-23428-x
En réponse à l’épidémie de COVID-19, l’Égypte a mis en place un modèle de soins unique basé sur des hôpitaux de quarantaine où seuls les patients confirmés atteints de COVID-19 et référés de l’extérieur étaient admis, et où les travailleurs de la santé résidaient en permanence pendant des quarts de travail d’une à deux semaines. À l’aide d’un modèle mathématique tenant compte des taux de faux négatifs des tests RT-PCR, nous avons calculé le taux d’incidence de l’infection par le SRAS-CoV-2 chez les travailleurs de la santé, tout en dévoilant la proportion d’infections non diagnostiquées malgré les tests de routine.
In response to the COVID-19 epidemic, Egypt established a unique care model based on quarantine hospitals where only externally-referred confirmed COVID-19 patients were admitted, and healthcare workers resided continuously over 1- to 2-week working shifts. Using a mathematical model accounting for the false-negative rates of RT-PCR tests, we computed the incidence rate of SARS-CoV-2 infection among HCWs, while unveiling the proportion of infections remaining undiagnosed despite routine testing. We relied on longitudinal data, including results of routine RT-PCR tests, collected within three Egyptian quarantine hospitals. We estimated an incidence rate (per 100 person-day, PD) of 1.05 (95% CrI 0.58–1.65) at Hospital 1, 1.92 (95% CrI 0.93–3.28) at Hospital 2 and 7.62 (95% CrI 3.47–13.70) at Hospital 3. We found that the risk for an HCW to be infected during a working shift lay within the range of risk levels previously documented in standard healthcare settings for Hospitals 1–2, whereas it was > threefold higher for Hospital 3. This large variation suggests that HCWs from quarantine hospitals may face a high occupational risk of infection, but that, with sufficient infection control measures, this risk can be brought down to levels similar to those observed in standard healthcare settings.