Source avec lien : JAMA Network Open, 5(5). 10.1001/jamanetworkopen.2022.10450
Le travail de nuit en rotation est associé à un taux de mortalité plus élevé. Pour cette étude de cohorte, un phénotype composite de vieillissement en bonne santé a été déterminé parmi 46 318 participants âgés de 46 à 68 ans et exempts de maladies chroniques majeures en 1988 lorsque l’historique du travail de nuit a été évalué. Dans une analyse secondaire dans laquelle le déclin des fonctions cognitives a été pris en compte dans la définition du vieillissement en bonne santé, 14 273 infirmières ont été impliquées.
Rotating night shift work is associated with higher mortality. Whether it is also associated with overall health among those who survive to older ages remains unclear.To examine whether rotating night shift work is associated with healthy aging after 24 years of follow-up in the Nurses’ Health Study, a cohort study among registered female nurses.For this cohort study, a composite healthy aging phenotype was ascertained among 46 318 participants who were aged 46 to 68 years and free of major chronic diseases in 1988 when the history of night shift work was assessed. In a secondary analysis in which cognitive function decline was considered in the healthy aging definition, 14 273 nurses were involved. Data were analyzed from March 1 to September 30, 2021.Duration of rotating night shift work.Healthy aging was defined as reaching at least 70 years of age and being free of 11 major chronic diseases, memory impairment, physical limitation, or deteriorated mental health.Of 46 318 female nurses (mean [SD] age at baseline, 55.4 [6.1] years), 3695 (8.0%) achieved healthy aging after 24 years of follow-up. After adjusting for established and potential confounders, compared with women who never worked rotating night shifts, the odds of achieving healthy aging decreased significantly with increasing duration of night shift work. The odds ratios were 0.96 (95% CI, 0.89-1.03) for 1 to 5 years, 0.92 (95% CI, 0.79-1.07) for 6 to 9 years, and 0.79 (95% CI, 0.69-0.91) for 10 or more years of night shift work (P = .001 for trend). This association did not differ substantially by age and lifestyles and was consistent for 4 individual dimensions of healthy aging. Results were similar in a secondary analysis, with an odds ratio of 0.73 (95% CI, 0.60-0.89; P < .001 for trend) comparing 10 or more years of night shift work vs no night shift work.In this cohort study, rotating night shift work was associated with decreased probability of healthy aging among US female nurses. These data support the notion that excess night shift work is a significant health concern that may also lead to deteriorated overall health among older individuals. Lisez l’article