Source avec lien : American Journal of Infection Control, (Prépublication). 10.1016/j.ajic.2021.11.001
Les travailleurs de la santé (TS) sont en première ligne pour le COVID-19. Une meilleure connaissance des facteurs de risque d’infection par le SRAS-CoV-2 est cruciale pour leur protection. Nous avons cherché à identifier ces facteurs de risque en nous concentrant sur les activités de soins. Nous avons mené une enquête de séroprévalence auprès des soignants dans un hôpital de référence français. Les données sur les expositions au COVID-19, les activités de soins et l’équipement de protection ont été recueillies par un questionnaire standardisé. Des régressions logistiques multivariées ont été utilisées pour évaluer les facteurs de risque pour les IgG du SRAS-CoV-2 ajustés sur les facteurs de confusion potentiels.
Background Health care workers (HCWs) are on the front line for COVID-19. Better knowledge of risk factors for SARS-CoV-2 infection is crucial for their protection. We aimed to identify these risk factors with a focus on care activities. Methods We conducted a seroprevalence survey among HCWs in a French referral hospital. Data on COVID-19 exposures, care activities, and protective equipment were collected on a standardized questionnaire. Multivariate logistic regressions were used to assess risk factors for SARS-CoV-2 IgG adjusted on potential confounding. Findings Among the 3,234 HCWs enrolled, the prevalence of SARS-CoV-2 IgG was 3.8%. Risk factors included contact with relatives or HCWs with COVID-19 (odds ratio [OR] 2.20 [1.40-3.45] and 2.16 [1.46-3.18], respectively), but not contact with COVID-19 patients. In multivariate analyses, suboptimal use of protective equipment during nasopharyngeal sampling (OR 3.46 [1.15-10.40]), mobilisation of patients in bed (OR 3.30 [1.51-7.25]), clinical examination (OR 2.51 [1.16-5.43]), and eye examination (OR 2.90 [1.01-8.35]) were associated with SARS-CoV-2 infection. Patients washing and dressing and aerosol-generating procedures were additional risk factors, with or without appropriate use of protective equipment (OR 1.37 [1.04-1.81] and 1.74 [1.05-2.88]). Conclusions Risk factors for SARS-CoV-2 infection among HCWs are (1) contact with relatives or HCWs with COVID-19, (2) close or prolonged contact with patients, (3) aerosol-generating procedures. Enhanced protective measures during the two latter care-activities may be warranted.