Occupation and risk of COVID-19: prospective cohort study of 120,621 UK Biobank participants

Source avec lien : Occupational & Environmental Health, , 5/23/2020. 10.1101/2020.05.22.20109892

Un article en prépublication, qui n’a pas encore fait l’objet d’une évaluation par les pairs, examine le risque de COVID-19 dans diverses professions. Les résultats de l’étude, menée au Royaume-Uni, montrent que les travailleurs de soutien au personnel médical, ainsi que les travailleurs sociaux, ont un risque plus élevé d’infection grave au SRAS-CoV-2. Les chercheurs ont souligné l’importance d’adopter des politiques nationales et organisationnelles pour protéger et soutenir les travailleurs qui présentent un risque élevé d’infection.

Objectives: To investigate COVID-19 risk by occupational group. Design: Prospective study of linked population-based and administrative data. Setting: UK Biobank data linked to SARS-CoV-2 test results from Public Health England from 16 March to 3 May 2020. Participants: 120,621 UK Biobank participants who were employed or self-employed at baseline (20062010) and were 65 years or younger in March 2020. Overall, 29% (n=37,890) were employed in essential occupational groups, which included healthcare workers, social and education workers, and ‘other’ essential workers comprising of police and protective service, food, and transport workers. Poisson regression models, adjusted for baseline sociodemographic, work-related, health, and lifestyle-related risk factors were used to assess risk ratios (RRs) of testing positive in hospital by occupational group as reported at baseline relative to non-essential workers. Main outcome measures: Positive SARS-CoV-2 test within a hospital setting (i.e. as an inpatient or in an Emergency Department). Results: 817 participants were tested for SARS-CoV-2 and of these, 206 (0.2%) individuals had a positive test in a hospital setting. Relative to non-essential workers, healthcare workers (RR 7.59, 95% CI: 5.43 to 10.62) and social and education workers (RR 2.17, 95% CI: 1.37 to 3.46) had a higher risk of testing positive for SARS-CoV-2 in hospital. Using more detailed groupings, medical support staff (RR 8.57, 95% CI: 4.35 to 16.87) and social care workers (RR 2.99, 95% CI: 1.71 to 5.24) had highest risk within the healthcare worker and social and education worker categories, respectively. In general, adjustment for covariates did not substantially change the pattern of occupational differences in risk. Conclusions: Essential workers in health and social care have a higher risk of severe SARS-CoV-2 infection. These findings underscore the need for national and organizational policies and practices that protect and support workers with elevated risk of SARS-CoV-2 infection.

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