Prolonged computer use by office workers induces ocular symptoms associated with tear film alterations and overexpression of mucin 5 AC and catalase

Source avec lien : Journal of Occupational and Environmental Medicine, (Prépublication). 10.1097/JOM.0000000000002653

L’objectif de cette étude était d’évaluer les symptômes du syndrome de vision informatique (CVS) chez les employés de bureau et les altérations du film lacrymal en fonction des heures d’utilisation quotidienne de l’ordinateur.

Objective  To evaluate office workers for symptoms of computer vision syndrome (CVS) and alterations in the tear film relate to the hours of daily computer use. Methods  Sixty-seven volunteers were divided into two groups: 2-6 h and 7-12 h of daily computer use. CVS symptoms, tear film stability by tear film break-up time (TBUT) test, and composition of mucin 5 AC, catalase, and IL-6 was assessed by relative gene expression of conjunctival impression cytology samples were examined. Results  All participants exhibited moderate symptoms of CVS, while 90% showed reduced tear film stability. For the 7-12 h (versus 2-6 h) group, these effects were more pronounced and overexpression of mucin 5 AC and catalase was detected. Conclusion  Prolonged computer use induced an overexpression of mucin 5 AC and catalase and instability of the tear film, associated with ocular symptoms.

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